Appendices
■141
6.A
TIME SCALE SEPARATION, EXAMPLE: SIR-UV MODEL
The singular perturbation technique has been applied to the SIR-UV model [42, 41].
The slow (S,I)-flow in Eqn. (6.4) occurs near a manifold that is a smooth surface in R3.
Letting ε = 0 in (6.2) determines the two-parameter nullspace for V in (6.4) consisting of
the critical manifold in (6.5).
M0 =
(S,I,V ) | V =
ϑMI
ϑI +νN , 0 ≤S ≤N, 0 ≤I ≤N
,
and one can demonstrate M0 is normally hyperbolic. Using M0 ’s local invariance, V can
be approximated by a power series
V = q0(S,I)+q1(S,I)ε+q2(S,I)ε2 +...,
0 < ε ≪1 .
q0(I) =
ϑMI
ϑI +νN
(QSSA approximation)
q1(S,I) = −νϑMN2
(ϑI +νN)3
β
M Sq0(I)−(γ +µ)I
q2(S,I) = νϑ2MN3βI
(ϑI +νN)5
µ(N −S)−β
M Sq0(I)
−
νϑMN2
(ϑI +νN)3 q1(S,I)
−νϑMN3
(γ +µ)(νN −2ϑI)
(ϑI +νN)5
−ϑβS(νN −3ϑI)
(ϑI +νN)6
β
M Sq0(I)−(γ +µ)I
The coefficients qi(S,I), i = 0,1,2 are computed from substitution of this equation invari-
ance criterion. With i = 0 we get the QSSA expression Eqn. (6.5). For more details the
reader is refered to [42, 41].